Hans Lehrach pioneered the development of cloning techniques, positional cloning and genome scale analysis techniques at Harvard Medical School (USA) and at the EMBL (Germany). He was involved from the beginning in the initial plans to sequence the human genome. At the ICRF (London), he developed innovative technologies and the first array-based robotics for genome wide gene function analyses and large-scale genome mapping, the core method behind the first human genome sequence. Since 1994 he has been director at the Max Planck Institute for Molecular Genetics (MPIMG, Berlin), carrying out pioneering work in functional genomics, genome sequencing, and cancer systems medicine. He is founder of multiple companies, including Sequana Therapeutics (San Diego), GPC Biotech (Munich-Martinsried) and Atlas Biolabs (Berlin).